发明公开
EP2383261A1 Process for the asymmetric hydrogenation of ketones
有权
Verfahren zur unfrischen Hydrierung von Ketonen
- 专利标题： Process for the asymmetric hydrogenation of ketones
- 专利标题（中）： Verfahren zur unfrischen Hydrierung von Ketonen
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申请号： EP10004348.8申请日： 2010-04-23
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公开(公告)号： EP2383261A1公开(公告)日： 2011-11-02
- 发明人: Wisdom, Richard , Jung, Jörg , Meudt, Andreas
- 申请人： Archimica GmbH
- 申请人地址： Brüningstrasse 50 65929 Frankfurt am Main DE
- 专利权人： Archimica GmbH
- 当前专利权人： Archimica GmbH
- 当前专利权人地址： Brüningstrasse 50 65929 Frankfurt am Main DE
- 代理机构： Schweitzer, Klaus
- 主分类号： C07D223/28
- IPC分类号： C07D223/28
摘要：
The invention relates to a process for the asymmetric transfer hydrogenation of a ketone substrate to produce as chiral secondary alcohol with an ee of greater than 85% in which an enantio-enriched chiral catalyst containing ruthenium or rhodium is used with a hydrogen donor and in which an anion exchange resin is used as a base.
公开/授权文献
- EP2383261B1 Process for the asymmetric hydrogenation of ketones 公开/授权日：2013-09-04
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