发明公开
EP2384328A1 6,7,8,9-TETRAHYDRO-5H-1,4,7,10A-TETRAAZA-CYCLOHEPT[F]INDENE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS, THEIR USE AND PROCESS FOR PREPARING THEM
有权
-6,7,8,9- TETRA HYDRO-5H-1,4,7,10A- TETRAAZACYCLOHEPT [f]茚衍生物，其药物组合物含有这些化合物，它们的用途和PROCESS FOR THEIR
- 专利标题： 6,7,8,9-TETRAHYDRO-5H-1,4,7,10A-TETRAAZA-CYCLOHEPT[F]INDENE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS, THEIR USE AND PROCESS FOR PREPARING THEM
- 专利标题（中）： -6,7,8,9- TETRA HYDRO-5H-1,4,7,10A- TETRAAZACYCLOHEPT [f]茚衍生物，其药物组合物含有这些化合物，它们的用途和PROCESS FOR THEIR
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申请号： EP09756757.2申请日： 2009-11-26
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公开(公告)号： EP2384328A1公开(公告)日： 2011-11-09
- 发明人: MUELLER, Stephan-Georg , BROWN, Christoper, John , HEIFETZ, Alexander , NOSSE, Bernd , PRESTLE, Juergen , PREVOST, Natacha , RUDOLF, Klaus , SCHEUERER, Stefan , SCHINDLER, Marcus , STENKAMP, Dirk , THOMAS, Leo , TYE, Heather
- 申请人： Boehringer Ingelheim International GmbH
- 申请人地址： Binger Strasse 173 55216 Ingelheim am Rhein DE
- 专利权人： Boehringer Ingelheim International GmbH
- 当前专利权人： Boehringer Ingelheim International GmbH
- 当前专利权人地址： Binger Strasse 173 55216 Ingelheim am Rhein DE
- 代理机构： Hammann, Heinz
- 优先权： EP08170154 20081127
- 国际公布： WO2010060952 20100603
- 主分类号： C07D487/14
- IPC分类号： C07D487/14 ; A61K31/519 ; A61P25/00 ; A61P3/00
摘要：
The present invention relates to compounds defined by formula (I), wherein the groups X, Y, W and R
1 to R
4 are defined as in claim 1, possessing valuable pharmacological activity. Particularly the compounds are agonists of the 5-HT2C receptor, and thus are suitable for treatment and prevention of diseases which can be influenced by inhibition of this receptor, such as metabolic and CNS-related disorders.
1 to R
4 are defined as in claim 1, possessing valuable pharmacological activity. Particularly the compounds are agonists of the 5-HT2C receptor, and thus are suitable for treatment and prevention of diseases which can be influenced by inhibition of this receptor, such as metabolic and CNS-related disorders.
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