发明公开
EP2386567A2 Mutants of cholesterol-dependent cytolysins and uses thereof
有权
MutantenvonlesterinabhängigenCytolysinen und Verwendungen davon
- 专利标题: Mutants of cholesterol-dependent cytolysins and uses thereof
- 专利标题(中): MutantenvonlesterinabhängigenCytolysinen und Verwendungen davon
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申请号: EP11174235.9申请日: 2008-04-14
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公开(公告)号: EP2386567A2公开(公告)日: 2011-11-16
- 发明人: Tweten, Rodney K.
- 申请人: The Board Of Regents Of The University Of Oklahoma
- 申请人地址: 660 Parrington Oval Room 119 Oklahoma City, OK 73019 US
- 专利权人: The Board Of Regents Of The University Of Oklahoma
- 当前专利权人: The Board Of Regents Of The University Of Oklahoma
- 当前专利权人地址: 660 Parrington Oval Room 119 Oklahoma City, OK 73019 US
- 代理机构: Stuttard, Garry Philip
- 优先权: US923281P 20070413
- 主分类号: C07K14/195
- IPC分类号: C07K14/195 ; C07K14/31 ; C07K14/32 ; C07K14/33 ; C12N15/31 ; A61K38/16
摘要:
Mutants of cholesterol-dependent cytolysins comprising at least one amino acid substitution in at least one of Loop 1, Loop 2, or Loop 3 of Domain 4, nucleic acids encoding such polypeptide mutants, and compositions and vaccines comprising such polypeptide mutants.
公开/授权文献
- EP2386567B1 Mutants of cholesterol-dependent cytolysins and uses thereof 公开/授权日:2014-10-29
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