发明公开
EP2393828A1 EXTENDED RECOMBINANT POLYPEPTIDES AND COMPOSITIONS COMPRISING SAME
有权
延伸的重组多肽和组合物THEREFORE
- 专利标题: EXTENDED RECOMBINANT POLYPEPTIDES AND COMPOSITIONS COMPRISING SAME
- 专利标题(中): 延伸的重组多肽和组合物THEREFORE
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申请号: EP10739085.8申请日: 2010-02-03
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公开(公告)号: EP2393828A1公开(公告)日: 2011-12-14
- 发明人: SCHELLENBERGER, Volker , SILVERMAN, Joshua , WANG, Chia-wei , SPINK, Benjamin , STEMMER, Willem, P. , GEETHING, Nathan , TO, Wayne , CLELAND, Jeffrey, L.
- 申请人: Amunix Operating Inc.
- 申请人地址: 500 Ellis Street Mountainview, CA 94043 US
- 专利权人: Amunix Operating Inc.
- 当前专利权人: Amunix Operating Inc.
- 当前专利权人地址: 500 Ellis Street Mountainview, CA 94043 US
- 代理机构: Kremer, Simon Mark
- 优先权: US236493P 20090824; US185112P 20090608; US149669P 20090203; US280955P 20091110; US243707P 20090918; US281109P 20091112; US268193P 20090608; US280956P 20091110; US236836P 20090825; US245490P 20090924
- 国际公布: WO2010091122 20100812
- 主分类号: C07K1/00
- IPC分类号: C07K1/00 ; C07K14/00 ; C07K17/00
摘要:
The present invention relates to compositions comprising biologically active proteins linked to extended recombinant polypeptide (XTEN), isolated nucleic acids encoding the compositions and vectors and host cells containing the same, and methods of using such compositions in treatment of glucose-related diseases, metabolic diseases, coagulation disorders, and growth hormone-related disorders and conditions.
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