发明授权
EP2408463B1 D-ARG-2'6'-DIMETHYLTYROSINE-LYS-PHE-NH2 FOR USE IN THE PREVENTION AND TREATMENT OF BURN INJURIES AND SECONDARY COMPLICATIONS
有权
D-Arg-2'6'-二甲基酪氨酸-LYS-PHE-NH2以防止和烧伤的治疗及相关继发性并发症
- 专利标题： D-ARG-2'6'-DIMETHYLTYROSINE-LYS-PHE-NH2 FOR USE IN THE PREVENTION AND TREATMENT OF BURN INJURIES AND SECONDARY COMPLICATIONS
- 专利标题（中）： D-Arg-2'6'-二甲基酪氨酸-LYS-PHE-NH2以防止和烧伤的治疗及相关继发性并发症
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申请号： EP10764805.7申请日： 2010-03-19
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公开(公告)号： EP2408463B1公开(公告)日： 2016-10-19
- 发明人: TOMPKINS, Ronald G. , TZIKA, A. Aria , RAHME, Laurence , YU, Yong-Ming , MARTYN, Jeevendra A.
- 申请人： The General Hospital Corporation d/b/a Massachusetts General Hospital
- 申请人地址： 55 Fruit Street Boston, MA 02114 US
- 专利权人： The General Hospital Corporation d/b/a Massachusetts General Hospital
- 当前专利权人： The General Hospital Corporation d/b/a Massachusetts General Hospital
- 当前专利权人地址： 55 Fruit Street Boston, MA 02114 US
- 代理机构： Lawrence, John
- 优先权： US162060P 20090320; US249658P 20091008; US258533P 20091105; US259349P 20091109
- 国际公布： WO2010120431 20101021
- 主分类号： A61K38/07
- IPC分类号： A61K38/07 ; A61P17/02
摘要：
The disclosure relates to methods for treating a subject suffering from a burn injury or associated complications by administering to the subject an effective amount of an aromatic-cationic peptide. For example, a burn injury may be associated with distant pathophysiological effects, such as hypermetabolism, skeletal muscle dysfunction, and organ damage. The disclosure also relates to methods for protecting a subject from a burn injury by administering an effective amount of an aromatic-cationic peptide to a subject at risk of a burn injury.
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