发明公开
- 专利标题： NOVEL ANTI-INFLAMMATORY AGENTS
- 专利标题（中）： 新型抗炎剂
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申请号： EP10714825.6申请日： 2010-04-21
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公开(公告)号： EP2421533A1公开(公告)日： 2012-02-29
- 发明人: HANSEN, Henrik, C. , WAGNER, Gregory, S. , ATTWELL, Sarah, C. , MCLURE, Kevin, G. , KULIKOWSKI, Ewelina, B.
- 申请人： RESVERLOGIX CORP.
- 申请人地址： 202, 279 Midpark Way S.E. Calgary, Alberta T2X 1M2 CA
- 专利权人： RESVERLOGIX CORP.
- 当前专利权人： RESVERLOGIX CORP.
- 当前专利权人地址： 202, 279 Midpark Way S.E. Calgary, Alberta T2X 1M2 CA
- 代理机构： Vossius & Partner
- 优先权： US171620P 20090422
- 国际公布： WO2010123975 20101028
- 主分类号： A61K31/47
- IPC分类号： A61K31/47 ; C07D239/91
摘要：
Disclosed are methods of regulating interleukin-6 (IL-6) and/or vascular cell adhesion molecule-1 (VCAM-1) and methods of treating and/or preventing cardiovascular and inflammatory diseases and related disease states, such as, for example, atherosclerosis, asthma, arthritis, cancer, multiple sclerosis, psoriasis, and inflammatory bowel diseases, and autoimmune disease(s) by administering a naturally occurring or synthetic quinazolone derivative. The invention provides novel synthetic quinazolone compounds, as well as pharmaceutical compositions comprising those compounds.
公开/授权文献
- EP2421533B1 NOVEL ANTI-INFLAMMATORY AGENTS 公开/授权日：2018-10-17
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