A digital printing signature production system S comprises: a plurality of digital printing devices D1, D2, D3, and D4, each of the plurality of digital printing devices D1, D2, D3, and D4 including a paper feeding unit 1 configured to supply a continuous paper and digital printing units 3 and 4 configured to perform printing on the continuous paper supplied from the paper feeding unit 1; a continuous paper guide unit L configured to cause printing-completed continuous papers W1, W2, W3, and W4 fed from the plurality of digital printing devices D1, D2, D3, and D4 and each having different content printed thereon to be overlapped such that width direction edges of the printing-completed continuous papers W1, W2, W3, and W4 are aligned, thereby forming a single continuous paper group Wg; and a single folding unit F configured such that the single continuous paper group Wg is guided into the single folding unit F to produce a signature.