发明公开
EP2427553A2 TREATMENT OF LIPID TRANSPORT AND METABOLISM GENE RELATED DISEASES BY INHIBITION OF NATURAL ANTISENSE TRANSCRIPT TO A LIPID TRANSPORT AND METABOLISM GENE
审中-公开
物质与LIPIDTRANSPORT- WECH SELGE相关疾病的反义自然科学成绩单针对LIPIDTRANSPORT-和物质WECH SELGEN阻垢处理
- 专利标题： TREATMENT OF LIPID TRANSPORT AND METABOLISM GENE RELATED DISEASES BY INHIBITION OF NATURAL ANTISENSE TRANSCRIPT TO A LIPID TRANSPORT AND METABOLISM GENE
- 专利标题（中）： 物质与LIPIDTRANSPORT- WECH SELGE相关疾病的反义自然科学成绩单针对LIPIDTRANSPORT-和物质WECH SELGEN阻垢处理
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申请号： EP10772845.3申请日： 2010-05-06
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公开(公告)号： EP2427553A2公开(公告)日： 2012-03-14
- 发明人: COLLARD, Joseph , KHORKOVA SHERMAN, Olga
- 申请人： Opko Curna, LLC
- 申请人地址： 4400 Biscayne Boulevard Miami, FL 33137 US
- 专利权人： Opko Curna, LLC
- 当前专利权人： Opko Curna, LLC
- 当前专利权人地址： 4400 Biscayne Boulevard Miami, FL 33137 US
- 代理机构： Evenson, Jane Harriet
- 优先权： US175930P 20090506; US176267P 20090507; US180646P 20090522; US235227P 20090819; US248212P 20091002
- 国际公布： WO2010129799 20101111
- 主分类号： C12N15/113
- IPC分类号： C12N15/113 ; C12N15/63 ; A61K31/713 ; A61K48/00
摘要：
The present invention relates to antisense oligonucleotides that modulate the expression of and/or function of a Lipid transport and metabolism gene, in particular, by targeting natural antisense polynucleotides of a Lipid transport and metabolism gene. The invention also relates to the identification of these antisense oligonucleotides and their use in treating diseases and disorders associated with the expression of a Lipid transport and metabolism genes.
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