发明公开
EP2428564A1 A HEPATITIS B VIRUS MUTATION STRAIN WITH RESISTANCE TO ADEFOVIR DIPIVOXIL AND THE USES THEREOF
审中-公开
HEPATITIS-B-VIRUS-MUTATIONSSTAMM MIT RESISTENZ GEGEN ADEFOVIR DIPIVOXIL UND VERWENDUNGEN DAVON
- 专利标题: A HEPATITIS B VIRUS MUTATION STRAIN WITH RESISTANCE TO ADEFOVIR DIPIVOXIL AND THE USES THEREOF
- 专利标题(中): HEPATITIS-B-VIRUS-MUTATIONSSTAMM MIT RESISTENZ GEGEN ADEFOVIR DIPIVOXIL UND VERWENDUNGEN DAVON
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申请号: EP09844226.2申请日: 2009-10-20
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公开(公告)号: EP2428564A1公开(公告)日: 2012-03-14
- 发明人: WEI, Lai , DU, Shaocai , LIU, Lijun , WANG, Jianghua
- 申请人: Peking University People's Hospital
- 申请人地址: Hepatology Institute No.11 Xizhimen South Street Beijing 100044 CN
- 专利权人: Peking University People's Hospital
- 当前专利权人: Peking University People's Hospital
- 当前专利权人地址: Hepatology Institute No.11 Xizhimen South Street Beijing 100044 CN
- 代理机构: Ricker, Mathias
- 优先权: CN200910083422 20090504
- 国际公布: WO2010127474 20101111
- 主分类号: C12N7/00
- IPC分类号: C12N7/00 ; C12Q1/70 ; C12Q1/68 ; C12N15/01 ; C12N15/51 ; C12R1/92
摘要:
A HBV mutation strain is provided, wherein rtE218G mutation occurs at the polymerase region of the mutation strain. The use of the HBV strain in screening anti-HBV drugs and related detection reagents used to detect rtE218G mutation are also provided.
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