发明公开
EP2435442A1 VERFAHREN ZUR HERSTELLUNG VON CEFTOBIPROL MEDOCARIL
有权
VERFAHREN ZUR HERSTELLUNG VON CEFTOBIPOL MEDOCARIL
- 专利标题: VERFAHREN ZUR HERSTELLUNG VON CEFTOBIPROL MEDOCARIL
- 专利标题(英): Method for the production of ceftobiprole medocaril
- 专利标题(中): VERFAHREN ZUR HERSTELLUNG VON CEFTOBIPOL MEDOCARIL
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申请号: EP10723985.7申请日: 2010-05-25
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公开(公告)号: EP2435442A1公开(公告)日: 2012-04-04
- 发明人: KREMMINGER, Peter , LUDESCHER, Johannes , STURM, Hubert
- 申请人: Sandoz AG
- 申请人地址: Lichtstrasse 35 4056 Basel CH
- 专利权人: Sandoz AG
- 当前专利权人: Sandoz AG
- 当前专利权人地址: Lichtstrasse 35 4056 Basel CH
- 代理机构: Altmann, Andreas
- 优先权: EP09161028 20090525
- 国际公布: WO2010136423 20101202
- 主分类号: C07D501/04
- IPC分类号: C07D501/04 ; C07D501/18 ; C07D501/56
摘要:
The invention relates to a method for the production of organic compounds, in particular sodium (6R,7R)-7-[(Z)-2-(5-amino-[1,2,4]thiadiazole-3-yl)-2-hydroxyimino-acetylamino]-8-oxo-3-[(E)-(R)-1'-(5-methyl-2-oxo-[1,3]-dioxol-4-ylmethoxycarbonyl)-2-oxo-[1,3']bipyrrolidinyl-3-ylidenemethyl]-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2 carboxylate (ceftobiprole medocaril). The invention also relates to a method for the production of compounds of the general formula (1) and of the general formula (2), to the compounds themselves, and to intermediates in the production process according to the invention.
公开/授权文献
- EP2435442B1 VERFAHREN ZUR HERSTELLUNG VON CEFTOBIPROL MEDOCARIL 公开/授权日:2016-01-13
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