发明授权
- 专利标题: MICRONEEDLE DEVICE
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申请号: EP10786220.3申请日: 2010-06-10
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公开(公告)号: EP2441437B1公开(公告)日: 2018-08-08
- 发明人: TERAHARA Takaaki , TOKUMOTO Seiji
- 申请人: Hisamitsu Pharmaceutical Co., Inc.
- 申请人地址: 408, Tashirodaikan-machi Tosu-shi, Saga 841-0017 JP
- 专利权人: Hisamitsu Pharmaceutical Co., Inc.
- 当前专利权人: Hisamitsu Pharmaceutical Co., Inc.
- 当前专利权人地址: 408, Tashirodaikan-machi Tosu-shi, Saga 841-0017 JP
- 代理机构: Grünecker Patent- und Rechtsanwälte PartG mbB
- 优先权: JP2009139582 20090610
- 国际公布: WO2010143689 20101216
- 主分类号: A61K9/00
- IPC分类号: A61K9/00 ; A61K47/10 ; A61K47/32 ; A61K47/34 ; A61K47/36 ; A61M37/00
摘要:
A coating agent has been applied to microneedles having a biodegradable resin, and a relation between its strength and performance has been clarified. As a result thereof, it has been found that the application of the coating agent to microneedles of a biodegradable resin having a predetermined strength or more, that is, a predetermined weight average molecular weight, allows the microneedles to have excellent performance. Further, it has been found that in regard to the coating agent, a predetermined type and amount thereof are also useful to demonstrate the performance. In view of this, when a microneedle device 1 is arranged so that at least a part of a microneedle array 2 provided with microneedles 3 made from polylactic acid having a weight average molecular weight of 40,000 or more is coated with a carrier containing physiologically active ingredients, it is possible to attain excellent migration characteristics of the physiologically active ingredients to a living body.
公开/授权文献
- EP2441437A1 MICRONEEDLE DEVICE 公开/授权日:2012-04-18
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