发明公开
EP2446025A4 KETOREDUCTASE-MEDIATED STEREOSELECTIVE ROUTE TO ALPHA CHLOROALCOHOLS
有权
KETOREDUKTASE-VERMITTELTER STEREOSELEKTIVER PFAD ZU ALPHA-CHLORALKOHOLEN
- 专利标题： KETOREDUCTASE-MEDIATED STEREOSELECTIVE ROUTE TO ALPHA CHLOROALCOHOLS
- 专利标题（中）： KETOREDUKTASE-VERMITTELTER STEREOSELEKTIVER PFAD ZU ALPHA-CHLORALKOHOLEN
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申请号： EP10797576申请日： 2010-06-22
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公开(公告)号： EP2446025A4公开(公告)日： 2016-04-06
- 发明人: BONG YONG KOY , VOGEL MICHAEL , COLLIER STEVEN JAMES , MITCHELL VESNA , MAVINAHALLI JAGADEESH
- 申请人： CODEXIS INC
- 专利权人： CODEXIS INC
- 当前专利权人： CODEXIS INC
- 优先权： US21916209 2009-06-22; US30305710 2010-02-10
- 主分类号： C12N9/02
- IPC分类号： C12N9/02 ; A61P7/04 ; C12N15/53
摘要：
The present disclosure relates to engineered ketoreductase polypeptides and uses thereof for the preparation of α chloroalcohols from α chloroketones. Also provided are polynucleotides encoding the engineered ketoreductase polypeptides and host cells capable of expressing the engineered ketoreductase polypeptides.
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