发明公开
- 专利标题： CRYSTALLINE FREEBASE FORMS OF A BIPHENYL COMPOUND
- 专利标题（中）： CRYSTAL游离碱联苯
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申请号： EP10732616.7申请日： 2010-07-14
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公开(公告)号： EP2453894A1公开(公告)日： 2012-05-23
- 发明人: WOOLLAM, Grahame
- 申请人： Theravance, Inc.
- 申请人地址： 901 Gateway Boulevard South San Francisco, CA 94080 US
- 专利权人： Theravance, Inc.
- 当前专利权人： Theravance, Inc.
- 当前专利权人地址： 901 Gateway Boulevard South San Francisco, CA 94080 US
- 代理机构： Scott, Susan Margaret
- 优先权： US225803P 20090715
- 国际公布： WO2011008809 20110120
- 主分类号： A61K31/445
- IPC分类号： A61K31/445 ; C07D401/12 ; A61P11/00
摘要：
The invention provides two crystalline freebase forms of biphenyl-2-ylcarbamic acid l-(2-{[4-(4-carbamoylpiperidin-l-yImethyl)benzoyl]methylamino}ethyl)piperidin-4- yl ester. The invention also provides pharmaceutical compositions comprising the crystalline freebase or prepared using the crystalline freebases; processes and intermediates for preparing the crystalline freebases; and methods of using the crystalline freebases to treat a pulmonary disorder.
公开/授权文献
- EP2453894B1 CRYSTALLINE FREEBASE FORM OF A BIPHENYL COMPOUND 公开/授权日：2015-11-04
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