- 专利标题: FENTANYL-CONTAINING ADHESIVE PREPARATION FOR EXTERNAL USE
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申请号: EP10802265.8申请日: 2010-07-21
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公开(公告)号: EP2457570B1公开(公告)日: 2018-08-22
- 发明人: NARUSE, Mamoru , HATTORI, Kenichi , MATSUSHITA, Kunihiko
- 申请人: Teikoku Seiyaku Co., Ltd.
- 申请人地址: 567 Sanbonmatsu Higashikagawa-shi, Kagawa 769-2695 JP
- 专利权人: Teikoku Seiyaku Co., Ltd.
- 当前专利权人: Teikoku Seiyaku Co., Ltd.
- 当前专利权人地址: 567 Sanbonmatsu Higashikagawa-shi, Kagawa 769-2695 JP
- 代理机构: Beckmann, Claus
- 优先权: JP2009173135 20090724
- 国际公布: WO2011010645 20110127
- 主分类号: A61K31/4468
- IPC分类号: A61K31/4468 ; A61K9/70 ; A61K47/06 ; A61K47/14 ; A61K47/32
摘要:
Disclosed is a fentanyl-containing adhesive preparation for external use, wherein an adhesive layer is laminated on a supporting body. The adhesive layer contains SIS, a tackifier resin that is composed of a rosin resin and terpene resin, and a softener that is composed of a plybutene and a liquid paraffin. The adhesive layer also contains fentanyl as an active ingredient. The fentanyl-containing adhesive preparation for external use has excellent skin permeation of fentanyl and high preparation stability, without suffering from crystallization of fentanyl during storage.
公开/授权文献
- EP2457570A1 FENTANYL-CONTAINING ADHESIVE PREPARATION FOR EXTERNAL USE 公开/授权日:2012-05-30
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