发明公开
EP2464228A4 SUBSTITUTED CYCLOPROPYL COMPOUNDS, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF TREATMENT
有权
取代的环丙基的化合物,其具有这样的化合物和治疗方法的组合物THAT
- 专利标题: SUBSTITUTED CYCLOPROPYL COMPOUNDS, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF TREATMENT
- 专利标题(中): 取代的环丙基的化合物,其具有这样的化合物和治疗方法的组合物THAT
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申请号: EP10808529申请日: 2010-08-03
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公开(公告)号: EP2464228A4公开(公告)日: 2013-01-23
- 发明人: WOOD HAROLD B , ADAMS ALAN D , SZEWCZYK JASON W , ZHANG YONG , YANG MENG
- 申请人: MERCK SHARP & DOHME
- 专利权人: MERCK SHARP & DOHME
- 当前专利权人: MERCK SHARP & DOHME
- 优先权: US23369009 2009-08-13
- 主分类号: A61K31/445
- IPC分类号: A61K31/445 ; A61P3/10 ; C07D401/04 ; C07D401/14 ; C07D413/14
摘要:
Substituted cyclopropyl compounds of the formula I: are disclosed as useful for treating or preventing type 2 diabetes and similar conditions. Pharmaceutically acceptable salts are included as well. The compounds are useful as agonists of the g-protein coupled receptor GPR-119.
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