发明公开
- 专利标题： FUSED HETEROCYCLIC COMPOUNDS AS ION CHANNEL MODULATORS
- 专利标题（中）： 简明杂环化合物AS离子通道调节剂
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申请号： EP10737724.4申请日： 2010-07-26
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公开(公告)号： EP2464645A1公开(公告)日： 2012-06-20
- 发明人: CORKEY, Britton , ELZEIN, Elfatih , JIANG, Robert , KALLA, Rao , KOBAYASHI, Tetsuya , KOLTUN, Dmitry , LI, Xiaofen , NOTTE, Gregory , PARKHILL, Eric , PERRY, Thao , ZABLOCKI, Jeff
- 申请人： Gilead Palo Alto, Inc.
- 申请人地址： 333 Lakeside Drive Foster City, CA 94404 US
- 专利权人： Gilead Palo Alto, Inc.
- 当前专利权人： Gilead Palo Alto, Inc.
- 当前专利权人地址： 333 Lakeside Drive Foster City, CA 94404 US
- 代理机构： Schnappauf, Georg
- 优先权： US360037P 20100630; US228864P 20090727
- 国际公布： WO2011014462 20110203
- 主分类号： C07D471/04
- IPC分类号： C07D471/04 ; A61K31/437 ; A61K31/519 ; A61K31/4985 ; A61K31/5025 ; A61P9/00
摘要：
The present invention relates to compounds that are sodium channel inhibitors and to their use in the treatment of various disease states, including cardiovascular diseases and diabetes. In particular embodiments, the structure of the compounds is given by Formula I: wherein W1, W2, W3, R1, Q, X1, X2 and X3 are as described herein, to methods for the preparation and use of the compounds and to pharmaceutical compositions containing the same.
公开/授权文献
- EP2464645B1 FUSED HETEROCYCLIC COMPOUNDS AS ION CHANNEL MODULATORS 公开/授权日：2017-07-05
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