发明公开
- 专利标题： UROCORTIN 2 ANALOGS AND USES THEREOF
- 专利标题（中）： 尿皮质素-2类似物及其用途
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申请号： EP10749982.4申请日： 2010-08-27
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公开(公告)号： EP2470560A1公开(公告)日： 2012-07-04
- 发明人: VALE, Wylie, W. , VAUGHAN, Joan , DONALDSON, Cindy , FISCHER, Wolfgang , RIVIER, Jean, E.
- 申请人： Research Development Foundation
- 申请人地址： 402 North Division Street Carson City, NV 89703 US
- 专利权人： Research Development Foundation
- 当前专利权人： Research Development Foundation
- 当前专利权人地址： 402 North Division Street Carson City, NV 89703 US
- 代理机构： Vossius & Partner
- 优先权： US237995P 20090828
- 国际公布： WO2011025905 20110303
- 主分类号： C07K14/575
- IPC分类号： C07K14/575
摘要：
Disclosed are polypeptides that are analogs of urocortin 2 that have pharmacological activity similar to urocortin 2 but have improved water solubility compared to urocortin 2, and pharmaceutical compositions of the polypeptides of the present invention. Also disclosed are polynucleotides encoding the polypeptides, and methods of treating pathophysiological states employing pharmaceutical compositions of the polypeptides and polynucleotides of the present invention. In addition, disclosed are vectors and host cells that include a nucleic acid encoding a polypeptide of the present invention, and kits that include pharmaceutical compositions of the present invention.
公开/授权文献
- EP2470560B1 UROCORTIN 2 ANALOGS AND USES THEREOF 公开/授权日：2015-06-10
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