发明公开
- 专利标题: FORMULATIONS COMPRISING TRIPTAN COMPOUNDS
- 专利标题(中): 包含TRIPTAN化合物的制剂
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申请号: EP10743228.8申请日: 2010-06-17
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公开(公告)号: EP2480197A2公开(公告)日: 2012-08-01
- 发明人: GANDHI, Rajesh , MANIKONDA, Sreekanth , JANA, Arun , KUNTE, Sameer, Shrinivas
- 申请人: Dr. Reddy's Laboratories Ltd.
- 申请人地址: 7-1-27 Ameerpet Hyderabad 500 016 Andhra Pradesh IN
- 专利权人: Dr. Reddy's Laboratories Ltd.
- 当前专利权人: Dr. Reddy's Laboratories Ltd.
- 当前专利权人地址: 7-1-27 Ameerpet Hyderabad 500 016 Andhra Pradesh IN
- 代理机构: Müller-Boré & Partner Patentanwälte
- 优先权: PCT/US2010/038838 20100616; US292206P 20100105; US292213P 20100105; US816904 20100616; INCH23372009 20090925; INCH26072009 20091027
- 国际公布: WO2011036521 20110331
- 主分类号: A61K9/00
- IPC分类号: A61K9/00 ; A61K31/40 ; A61K31/70 ; A61K47/26
摘要:
The invention provides a pharmaceutical composition for intranasal administration comprising a salt of sumatriptan or a physiologically acceptable solvate thereof, an alkyl glycoside or saccharide alkyl ester and optionally at least one pharmaceutically acceptable excipient, wherein the said composition provides Tmax value of less than 30 minutes upon said administration. Other aspects and embodiments are contemplated and described. The invention also provides a pharmaceutical composition for intranasal administration comprising a triptan, a pharmaceutically acceptable vehicle and a mucosal permeation enhancer, wherein upon said administration said composition provides a Tmax substantially equivalent to subcutaneous administration of said triptan. Other aspects and embodiments are contemplated and described.
公开/授权文献
- EP2480197B1 FORMULATIONS COMPRISING TRIPTAN COMPOUNDS 公开/授权日:2015-11-11
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