发明公开
EP2482837A2 USE OF PROTEIN KINASE C DELTA (PKCD) INHIBITORS TO TREAT DIABETES, OBESITY, AND HEPATIC STEATOSIS
审中-公开
蛋白激酶C-DELTA(PKCD-)抑制剂在糖尿病,肥胖症和脂肪肝治疗中的用途
- 专利标题: USE OF PROTEIN KINASE C DELTA (PKCD) INHIBITORS TO TREAT DIABETES, OBESITY, AND HEPATIC STEATOSIS
- 专利标题(中): 蛋白激酶C-DELTA(PKCD-)抑制剂在糖尿病,肥胖症和脂肪肝治疗中的用途
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申请号: EP10821157.4申请日: 2010-09-29
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公开(公告)号: EP2482837A2公开(公告)日: 2012-08-08
- 发明人: KAHN, C. Ronald , BEZY, Olivier
- 申请人: Joslin Diabetes Center, Inc.
- 申请人地址: One Joslin Place Boston, MA 02215 US
- 专利权人: Joslin Diabetes Center, Inc.
- 当前专利权人: Joslin Diabetes Center, Inc.
- 当前专利权人地址: One Joslin Place Boston, MA 02215 US
- 代理机构: Williams, Gareth Owen
- 优先权: US246821P 20090929
- 国际公布: WO2011041385 20110407
- 主分类号: A61K38/16
- IPC分类号: A61K38/16 ; A61K38/17 ; A61K31/7105 ; A61K31/7088 ; A61P3/04 ; A61P3/10
摘要:
Described are methods of improving insulin sensitivity, and treating fatty liver disease (including non-alcoholic steatohepatitis (NASH)), by administering specific inhibitors of PKC delta.
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