发明公开
EP2485713A1 LIQUID PRECURSOR COMPOSITIONS AND USES THEREOF FOR A PH-DEPENDANT SUSTAINED RELEASE TREATMENT OF ORAL DISORDERS
审中-公开
液态前体组合物及其应用对于pH依赖治疗口腔疾病持续释放
- 专利标题： LIQUID PRECURSOR COMPOSITIONS AND USES THEREOF FOR A PH-DEPENDANT SUSTAINED RELEASE TREATMENT OF ORAL DISORDERS
- 专利标题（中）： 液态前体组合物及其应用对于pH依赖治疗口腔疾病持续释放
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申请号： EP10784350.0申请日： 2010-10-05
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公开(公告)号： EP2485713A1公开(公告)日： 2012-08-15
- 发明人: FRIEDMAN, Michael , STEINBERG, Doron , GATI, Irith
- 申请人： Yissum Research Development Company of the Hebrew University of Jerusalem
- 申请人地址： Hi-Tech Park, Edmond J. Safra Campus Givat-Ram P.O. Box 39135 Jerusalem 91390 IL
- 专利权人： Yissum Research Development Company of the Hebrew University of Jerusalem
- 当前专利权人： Yissum Research Development Company of the Hebrew University of Jerusalem
- 当前专利权人地址： Hi-Tech Park, Edmond J. Safra Campus Givat-Ram P.O. Box 39135 Jerusalem 91390 IL
- 代理机构： Harmsen, Dirk
- 优先权： US248544P 20091005
- 国际公布： WO2011042897 20110414
- 主分类号： A61K9/08
- IPC分类号： A61K9/08 ; A61K9/70 ; A61K9/12 ; A61C8/00 ; A61K6/08 ; A61Q11/00
摘要：
The present invention discloses liquid precursor compositions adapted for application on a hard surface in the oral cavity, comprising at least one therapeutic agent suitable for the treatment of oral disorders, at least one acidic-pH sensitive polymer, at least one hydrophobic polymer, and a pharmaceutically acceptable volatile carrier, wherein a weight ratio between said at least one hydrophobic polymer and said at least one acidic-pH sensitive polymer is larger than 1. The invention also discloses formulations formed of the solidification of these compositions, and methods for treating oral disorders by applying these compositions on hard surfaces in the oral cavity or to be placed in the oral cavity.
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