- 专利标题： MONOCLONAL ANTIBODIES TO PROGASTRIN AND THEIR USES
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申请号： EP10768878.0申请日： 2010-10-15
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公开(公告)号： EP2488551B1公开(公告)日： 2018-07-25
- 发明人: PANNEQUIN, Julie , BOUDIER, Laure , JOUBERT, Dominique , HOLLANDE, Frédéric
- 申请人： Progastrine et Cancers S.à r.l. , Institut National de la Santé et de la Recherche Médicale (INSERM) , Centre National de la Recherche Scientifique (C.N.R.S.)
- 申请人地址： 11, Côte d'Eich 1450 Luxembourg LU
- 专利权人： Progastrine et Cancers S.à r.l.,Institut National de la Santé et de la Recherche Médicale (INSERM),Centre National de la Recherche Scientifique (C.N.R.S.)
- 当前专利权人： Progastrine et Cancers S.à r.l.,Institut National de la Santé et de la Recherche Médicale (INSERM),Centre National de la Recherche Scientifique (C.N.R.S.)
- 当前专利权人地址： 11, Côte d'Eich 1450 Luxembourg LU
- 代理机构： Regimbeau
- 优先权： US252625P 20091016
- 国际公布： WO2011045080 20110421
- 主分类号： C07K16/26
- IPC分类号： C07K16/26
摘要：
The present disclosure is directed to progastrin monoclonal antibodies, fragments thereof, compositions comprising progastrin monoclonal antibodies, and methods of making and using progastrin monoclonal antibodies and compositions thereof. The present disclosure is directed to methods of treating colorectal cancer with progastrin monoclonal antibodies and compositions comprising progastrin monoclonal antibodies or fragments thereof. The present disclosure is further directed to methods comprising detection of progastrin, including methods of diagnosing colorectal cancer and methods of monitoring efficacy of anti-cancer therapy in subjects suffering from colorectal cancer.
公开/授权文献
- EP2488551A2 MONOCLONAL ANTIBODIES TO PROGASTRIN AND THEIR USES 公开/授权日：2012-08-22
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