发明公开
- 专利标题： RAF INHIBITOR COMPOUNDS AND METHODS OF USE THEREOF
- 专利标题（中）： RAF抑制剂化合物及其使用方法
-
申请号： EP10805862.9申请日： 2010-08-27
-
公开(公告)号： EP2493865A2公开(公告)日： 2012-09-05
- 发明人: ALIAGAS, Ignacio , GRADL, Stefan , GUNZNER, Janet , LEE, Wendy , MATHIEU, Simon , RUDOLPH, Joachim , WEN, Zhaoyang , ZHAO, Guiling , BUCKMELTER, Alexandre J. , GRINA, Jonas , HANSEN, Joshua D. , LAIRD, Ellen , MORENO, David , REN, Li , WENGLOWSKY, Steven Mark
- 申请人： Array Biopharma, Inc. , Genentech, Inc.
- 申请人地址： 3200 Walnut Street Boulder, CO 80301 US
- 专利权人： Array Biopharma, Inc.,Genentech, Inc.
- 当前专利权人： Array Biopharma, Inc.,Genentech, Inc.
- 当前专利权人地址： 3200 Walnut Street Boulder, CO 80301 US
- 优先权： US238105P 20090828; US312448P 20100310
- 国际公布： WO2011025938 20110303
- 主分类号： C07D239/94
- IPC分类号： C07D239/94 ; C07D403/12 ; C07D405/12 ; C07D471/04 ; A61K31/517 ; A61K31/519 ; A61P35/00
摘要：
Compounds of Formula I are useful for inhibition of Raf kinases. Methods of using compounds of Formula I and stereoisomers, tautomers, prodrugs and pharmaceutically acceptable salts thereof,
for in vitro, in situ , and
in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions are disclosed.
for in vitro, in situ , and
in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions are disclosed.
信息查询
