发明公开
- 专利标题: Compositions and Methods for Treating Vascular Permeability
- 专利标题(中): 组合物和方法用于治疗血管通透性的
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申请号: EP11187344.4申请日: 2006-02-16
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公开(公告)号: EP2500031A3公开(公告)日: 2012-12-26
- 发明人: Feener, Edward P. , Aiello, Lloyd P
- 申请人: Joslin Diabetes Center, Inc.
- 申请人地址: One Joslin Place Boston, MA 02115 US
- 专利权人: Joslin Diabetes Center, Inc.
- 当前专利权人: Joslin Diabetes Center, Inc.
- 当前专利权人地址: One Joslin Place Boston, MA 02115 US
- 代理机构: Schlich, George William
- 优先权: US656167P 20050224; US725820P 20051012
- 主分类号: A61K38/17
- IPC分类号: A61K38/17 ; C12Q1/25 ; C12Q1/68 ; C12Q1/527 ; G01N33/68 ; A61P9/10
摘要:
Retinal vascular permeability is reduced in the eye by administration of an inhibitor of Carbonic Anhydrase-1 (CA-1) and/or Carbonic Anhydrase-2 (CA-2) and optionally an inhibitor of Vascular Endothelial Growth Factor (VEG) signalling. Compounds and methods are provided for diagnosis and treatment of associated disorders in retina and brain.
公开/授权文献
- EP2500031A2 Compositions and Methods for Treating Vascular Permeability 公开/授权日:2012-09-19
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