发明公开
- 专利标题： TRIAZOLOPYRIDINES
- 专利标题（中）： 三唑
-
申请号： EP10787274.9申请日： 2010-11-17
-
公开(公告)号： EP2507235A1公开(公告)日： 2012-10-10
- 发明人: SCHULZE, Volker , KOPPITZ, Marcus , KOSEMUND, Dirk , SCHIROK, Hartmut , BADER, Benjamin , LIENAU, Philip , WENGNER, Antje, Margret , BRIEM, Hans , HOLTON, Simon , SIEMEISTER, Gerhard , PRECHTL, Stefan , BÖMER, Ulf
- 申请人： Bayer Intellectual Property GmbH
- 申请人地址： Alfred-Nobel-Strasse 10 40789 Monheim DE
- 专利权人： Bayer Intellectual Property GmbH
- 当前专利权人： Bayer Intellectual Property GmbH
- 当前专利权人地址： Alfred-Nobel-Strasse 10 40789 Monheim DE
- 代理机构： Bayer Intellectual Property GmbH
- 优先权： EP09075535 20091130
- 国际公布： WO2011063908 20110603
- 主分类号： C07D471/04
- IPC分类号： C07D471/04 ; A61K31/437 ; A61P35/00
摘要：
The present invention relates to triazolopyridine compounds of general formula (I) which are Monopolar Spindle 1 kinase (Mps-1 or TTK) inhibitors: Formula (I), in which R
1 , R
2 , R
3 , R
4 , and R
5 are as given in the description and in the claims, to methods of preparing said compounds, to pharmaceutical compositions and combinations comprising said compounds, to the use of said compounds for manufacturing a pharmaceutical composition for the treatment or prophylaxis proliferative of diseases, as well as to intermediate compounds useful in the preparation of said compounds.
1 , R
2 , R
3 , R
4 , and R
5 are as given in the description and in the claims, to methods of preparing said compounds, to pharmaceutical compositions and combinations comprising said compounds, to the use of said compounds for manufacturing a pharmaceutical composition for the treatment or prophylaxis proliferative of diseases, as well as to intermediate compounds useful in the preparation of said compounds.
公开/授权文献
- EP2507235B1 TRIAZOLOPYRIMIDINES 公开/授权日：2014-10-22
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