发明公开
EP2519254A2 EXOSOMES DERIVED FROM RETICULOCYTES INFECTED WITH PLASMODIUM SP., METHOD FOR OBTAINING THEM AND USES THEREOF
有权
关氏疟原虫SP：衍生外来体感染性网状细胞，方法及其获得和它们的用途
- 专利标题： EXOSOMES DERIVED FROM RETICULOCYTES INFECTED WITH PLASMODIUM SP., METHOD FOR OBTAINING THEM AND USES THEREOF
- 专利标题（中）： 关氏疟原虫SP：衍生外来体感染性网状细胞，方法及其获得和它们的用途
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申请号： EP10800764.2申请日： 2010-12-28
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公开(公告)号： EP2519254A2公开(公告)日： 2012-11-07
- 发明人: DEL PORTILLO OBANDO, Hernando, Antonio , MARTIN JAULAR, Lorena , DEL FERNANDEZ BECERRA, María, Carmen
- 申请人： Centre De Recerca En Salut Internacional De Barcelona , Institució Catalana de Recerca i Estudis Avançats , Fundació Cellex , Hospital Clinic i Provincial de Barcelona
- 申请人地址： C/ Villarroel 170 08036 Barcelona ES
- 专利权人： Centre De Recerca En Salut Internacional De Barcelona,Institució Catalana de Recerca i Estudis Avançats,Fundació Cellex,Hospital Clinic i Provincial de Barcelona
- 当前专利权人： Centre De Recerca En Salut Internacional De Barcelona,Institució Catalana de Recerca i Estudis Avançats,Fundació Cellex,Hospital Clinic i Provincial de Barcelona
- 当前专利权人地址： C/ Villarroel 170 08036 Barcelona ES
- 代理机构： Carpintero Lopez, Francisco
- 优先权： ES200931275 20091228
- 国际公布： WO2011080271 20110707
- 主分类号： A61K39/015
- IPC分类号： A61K39/015
摘要：
The present invention belongs to the field of vaccines for the prevention and prophylaxis against malaria, more specifically it relates to exosomes isolated from reticulocytes infected with Plasmodium sp., to methods for obtaining them and to the use thereof for the prevention and prophylaxis against malaria as well as to its use for the discovery and identification of novel Plasmodium antigens. The invention also refers to artificial exosomes comprising Plasmodium sp. antigens. Finally, the invention refers to specific antigens discovered by means of the exosomes obtained from reticulocytes infected with Plasmodium sp.
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