发明授权
- 专利标题： Reduction of off-target RNA interference toxicity
- 专利标题（中）： 减少脱靶RNA干扰毒性
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申请号： EP12176494.8申请日： 2008-05-29
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公开(公告)号： EP2530152B1公开(公告)日： 2017-12-27
- 发明人: Davidson, Beverly L. , Mas Monteys, Alejandro , McBride, Jodi L. , Boudreau, Ryan
- 申请人： University of Iowa Research Foundation
- 申请人地址： Iowa Centers for Enterprise 2600 University Capitol Centre Iowa City, IA 52242-5500 US
- 专利权人： University of Iowa Research Foundation
- 当前专利权人： University of Iowa Research Foundation
- 当前专利权人地址： Iowa Centers for Enterprise 2600 University Capitol Centre Iowa City, IA 52242-5500 US
- 代理机构： D Young & Co LLP
- 优先权： US932468P 20070531; US38685P 20080321; US70622P 20080325; US111025P 20080428
- 主分类号： C12N15/113
- IPC分类号： C12N15/113 ; A61K31/713
摘要：
The present invention is directed to RNA interference (RNAi) molecules targeted against a nucleic acid sequence, and methods of using these RNAi molecules to reduce off-target toxicity.
公开/授权文献
- EP2530152A1 Reduction of off-target RNA interference toxicity 公开/授权日：2012-12-05
信息查询
IPC分类:
