发明公开
EP2533804A1 ANTIBODY DRUG CONJUGATES (ADC) THAT BIND TO 161P2F10B PROTEINS
有权
AN 161P2F10B - 蛋白结合的抗体药物偶联物(ADC)
- 专利标题: ANTIBODY DRUG CONJUGATES (ADC) THAT BIND TO 161P2F10B PROTEINS
- 专利标题(中): AN 161P2F10B - 蛋白结合的抗体药物偶联物(ADC)
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申请号: EP11740529.0申请日: 2011-02-08
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公开(公告)号: EP2533804A1公开(公告)日: 2012-12-19
- 发明人: TORGOV, Michael , MORRISON, Robert, Kendall , JAKOBOVITS, Aya , GUDAS, Jean , AN, Zili
- 申请人: Agensys, Inc.
- 申请人地址: 2225 Colorado Boulevard Santa Monica, CA 90404 US
- 专利权人: Agensys, Inc.
- 当前专利权人: Agensys, Inc.
- 当前专利权人地址: 2225 Colorado Boulevard Santa Monica, CA 90404 US
- 代理机构: Höglund, Lars
- 优先权: US302489P 20100208
- 国际公布: WO2011097627 20110811
- 主分类号: A61K39/00
- IPC分类号: A61K39/00
摘要:
Antibody drug conjugates (ADC's) that bind to 161P2F10B protein are described herein. 161P2F10B exhibits tissue specific expression in normal adult tissue, and is aberrantly expressed in the cancers listed in Table I. Consequently, the ADC's of the invention provide a therapeutic composition for the treatment of cancer.
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