发明公开
- 专利标题： Polymeric Tissue Sealant
- 专利标题（中）： Polymergewebeversiegelungsmittel
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申请号： EP12153260.0申请日： 2008-04-14
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公开(公告)号： EP2537539A1公开(公告)日： 2012-12-26
- 发明人: Rehor, Annemie , Cerritelli, Simona
- 申请人： Kuros Biosurgery AG
- 申请人地址： Technoparkstrasse 1 8005 Zürich CH
- 专利权人： Kuros Biosurgery AG
- 当前专利权人： Kuros Biosurgery AG
- 当前专利权人地址： Technoparkstrasse 1 8005 Zürich CH
- 代理机构： Hepp Wenger Ryffel AG
- 优先权： US911737P 20070413
- 主分类号： A61L15/58
- IPC分类号： A61L15/58 ; A61L31/02 ; C08L71/02
摘要：
Methods for making biomaterials for use as a tissue sealant, kits containing precursors for forming the biomaterials, and the resulting biomaterials are described herein. The biomaterials are formed from a composition comprising at least a first and a second precursor molecule, wherein:
i) the first precursor molecule is a poly(ethylene glycol) based polymer having x nucleophilic groups selected from the group consisting of thiol or amino groups, wherein x is equal to 2 or greater than 2, preferably 3, 4, 5, 6, 7 or 8;
ii) the second precursor molecule is of the general formula:
A-[(C 3 H 6 O) n -(C 2 H 4 O) m -B] i
wherein m and n are integers from 1 to 200
i is greater than 2, preferably 3, 4, 5, 6, 7 or 8
A is a branch point
B is a conjugated unsaturated group.
i) the first precursor molecule is a poly(ethylene glycol) based polymer having x nucleophilic groups selected from the group consisting of thiol or amino groups, wherein x is equal to 2 or greater than 2, preferably 3, 4, 5, 6, 7 or 8;
ii) the second precursor molecule is of the general formula:
A-[(C 3 H 6 O) n -(C 2 H 4 O) m -B] i
wherein m and n are integers from 1 to 200
i is greater than 2, preferably 3, 4, 5, 6, 7 or 8
A is a branch point
B is a conjugated unsaturated group.
公开/授权文献
- EP2537539B1 Polymeric Tissue Sealant 公开/授权日：2019-04-03
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