发明公开
- 专利标题： ANTIGEN BINDING PROTEINS SPECIFIC FOR SERUM AMYLOID P COMPONENT
- 专利标题（中）： 血清淀粉样P成分特异性抗原结合蛋白
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申请号： EP11705617.6申请日： 2011-03-01
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公开(公告)号： EP2542261A1公开(公告)日： 2013-01-09
- 发明人: BHINDER, Tejinder, Kaur , FORD, Susannah, Karen , GERMASCHEWSKI, Volker , LEWIS, Alan, Peter , PEPYS, Mark, Brian
- 申请人： Glaxo Group Limited
- 申请人地址： Glaxo Wellcome House Berkeley Avenue Greenford Middlesex UB6 0NN GB
- 专利权人： Glaxo Group Limited
- 当前专利权人： Glaxo Group Limited
- 当前专利权人地址： Glaxo Wellcome House Berkeley Avenue Greenford Middlesex UB6 0NN GB
- 代理机构： Chiappinelli, Susan Ann
- 优先权： US309957P 20100303
- 国际公布： WO2011107480 20110909
- 主分类号： A61K39/395
- IPC分类号： A61K39/395 ; A61P25/28 ; C07K16/18
摘要：
The present invention relates to antigen binding proteins, such as antibodies, which bind to serum amyloid P component (SAP), polynucleotides encoding such antigen binding proteins, pharmaceutical compositions comprising said antigen binding proteins and methods of manufacture. The present invention also concerns the use of such antigen binding proteins in the treatment or prophylaxis of diseases associated with amyloid deposition including systemic amyloidosis, local amyloidosis, Alzheimer's disease, and type 2 diabetes.
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