发明公开
EP2554161A1 Pharmaceutical composition comprising factor VII encapsulated in micelles
审中-公开
Pharmazutische Zusammensetzung entmaltend Faktor VII在Mizellen verkapselt
- 专利标题： Pharmaceutical composition comprising factor VII encapsulated in micelles
- 专利标题（中）： Pharmazutische Zusammensetzung entmaltend Faktor VII在Mizellen verkapselt
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申请号： EP11176276.1申请日： 2011-08-02
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公开(公告)号： EP2554161A1公开(公告)日： 2013-02-06
- 发明人: Perret, Gérald , Chtourou, Sami , Bihoreau, Nicolas
- 申请人： LFB Biotechnologies , NanoCarrier Co., Ltd.
- 申请人地址： 3 Avenue des Tropiques ZA de Courtaboeuf 91940 Les Ulis FR
- 专利权人： LFB Biotechnologies,NanoCarrier Co., Ltd.
- 当前专利权人： LFB Biotechnologies,NanoCarrier Co., Ltd.
- 当前专利权人地址： 3 Avenue des Tropiques ZA de Courtaboeuf 91940 Les Ulis FR
- 代理机构： Le Coupanec, Pascale A.M.P.
- 主分类号： A61K9/107
- IPC分类号： A61K9/107 ; A61K38/36 ; A61K47/34 ; A61K9/00 ; A61P7/04
摘要：
The invention relates to a pharmaceutical composition comprising factor VII encapsulated in micelles formed from block copolymer molecules containing (i) a hydrophilic polymer segment consisting of a polyalkylene glycol and (ii) a hydrophobic polymer segment consisting of a polyamino acid, with said polyamino acid comprising exclusively amino acid residues selected from the goup consisting of histidine, lysine, aspartic acid and glutamic acid residues, wherein a part of said amino acid residues is substituted with a hydrophobic group.
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