发明公开
- 专利标题： PHARMACEUTICAL COMPOSITIONS AND ADMINISTRATIONS THEREOF
- 专利标题（中）： 药物组合物及其施用
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申请号： EP11718596.7申请日： 2011-04-22
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公开(公告)号： EP2560649A1公开(公告)日： 2013-02-27
- 发明人: VAN GOOR, Fredrick, F. , ALARGOVA, Rossitza, Gueorguieva , ALCACIO, Tim, Edward , AREKAR, Sneha, G. , JOHNSTON, Steven, C. , KADIYALA, Irina, Nikolaevna , KESHAVARZ-SHOKRI, Ali , KRAWIEC, Mariusz , LEE, Elaine, Chungmin , MEDEK, Ales , MUDUNURI, Praveen , SULLIVAN, Mark, Jeffrey , ZAMAN, Noreen, Tasneem , ZHANG, Beili , ZHANG, Yuegang , ZLOKARNIK, Gregor
- 申请人： Vertex Pharmaceuticals Incorporated
- 申请人地址： 130 Waverly Street Cambridge, MA 02139 US
- 专利权人： Vertex Pharmaceuticals Incorporated
- 当前专利权人： Vertex Pharmaceuticals Incorporated
- 当前专利权人地址： 130 Waverly Street Cambridge, MA 02139 US
- 代理机构： Cohausz & Florack
- 优先权： US329510P 20100429; US327078P 20100422; US327091P 20100422
- 国际公布： WO2011133951 20111027
- 主分类号： A61K31/4704
- IPC分类号： A61K31/4704 ; A61K31/404 ; A61K31/443
摘要：
The present invention relates to pharmaceutical compositions comprising a compound of Formula I in combination with one or both of a Compound of Formula II and/or a Compound of Formula III. The invention also relates to solid forms and to pharmaceutical formulations thereof, and to methods of using such compositions in the treatment of CFTR mediated diseases, particularly cystic fibrosis.
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