发明公开
- 专利标题: SOLID ORAL DOSAGE FORMS COMPRISING TADALAFIL
- 专利标题(中): 包含TADALAFIL的固体口服剂型
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申请号: EP11774495.3申请日: 2011-04-22
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公开(公告)号: EP2563346A1公开(公告)日: 2013-03-06
- 发明人: ZERBE, Horst , PAIEMENT, Nadine , ANGUSTI, Angela , LONG, Cormac
- 申请人: Intelgenx Corporation
- 申请人地址: 6425 Abrams Saint-Laurent, QC H4S 1X9 CA
- 专利权人: Intelgenx Corporation
- 当前专利权人: Intelgenx Corporation
- 当前专利权人地址: 6425 Abrams Saint-Laurent, QC H4S 1X9 CA
- 代理机构: Grünecker, Kinkeldey, Stockmair & Schwanhäusser
- 优先权: US79348 20110404; US327969P 20100426
- 国际公布: WO2011135426 20111103
- 主分类号: A61K9/70
- IPC分类号: A61K9/70 ; A61K31/4985
摘要:
Improved pharmaceutical solid oral dosage forms for the buccal and/or sublingual delivery of Tadalafil. The improved delivery systems for solubilizing and stabilizing pharmaceutically active ingredients exhibit enhanced methods of preparation by the use improved solubilization systems which can maintain the Tadalafil in a buccal and/or sublingual oral dosage form or a polymeric film matrix that provides improved bioavailability and/or absorption of Tadalafil.
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