发明公开
- 专利标题： Molecular targets and compounds, and methods to identify the same, useful in the treatment of bone and joint degenerative diseases
- 专利标题（中）： 分子靶和化合物，以及用于它们的识别退行性骨关节疾病的治疗方法
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申请号： EP12183326.3申请日： 2008-06-19
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公开(公告)号： EP2565649A1公开(公告)日： 2013-03-06
- 发明人: Brys, Reginald Christophe Xavier , Vandeghinste, Nick Ernest René
- 申请人： Galapagos N.V.
- 申请人地址： Generaal de Wittelaan L11 A3 2800 Mechelen BE
- 专利权人： Galapagos N.V.
- 当前专利权人： Galapagos N.V.
- 当前专利权人地址： Generaal de Wittelaan L11 A3 2800 Mechelen BE
- 代理机构： Nichol, Maria Zenarosa
- 优先权： US936569P 20070620
- 主分类号： G01N33/68
- IPC分类号： G01N33/68 ; C12N15/11
摘要：
The present invention relates to methods for identifying agents capable of inhibiting the expression or activity of proteins involved in the processes modulating osteoclastogenesis, which inhibition is useful in the prevention and / or treatment of bone and joint degenerative diseases and diseases involving aberrant activity or differentiation of osteoclasts. In particular, the present invention provides methods for identifying agents for use in the prevention and / or treatment of rheumatoid arthritis.
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