发明公开
EP2570133A1 Glucagon analogs exhibiting physiological solubility and stability
有权
Glucagonanaloga mit生理学家LöslichkeitundStabilität
- 专利标题: Glucagon analogs exhibiting physiological solubility and stability
- 专利标题(中): Glucagonanaloga mit生理学家LöslichkeitundStabilität
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申请号: EP12163977.7申请日: 2006-11-06
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公开(公告)号: EP2570133A1公开(公告)日: 2013-03-20
- 发明人: Dimarchi, Richard , Smiley, David
- 申请人: Indiana University Research and Technology Corporation
- 申请人地址: 351 West 10th Street Indianapolis, IN 46202 US
- 专利权人: Indiana University Research and Technology Corporation
- 当前专利权人: Indiana University Research and Technology Corporation
- 当前专利权人地址: 351 West 10th Street Indianapolis, IN 46202 US
- 代理机构: Elsy, David
- 优先权: US734307P 20051107
- 主分类号: A61K38/00
- IPC分类号: A61K38/00
摘要:
Modified glucagon peptides are disclosed having improved solubility and stability, wherein the native glucagon has been modified by pegylation or the addition of a carboxy terminal peptide selected from the group consisting of SEQ ID No: 19, SEQ ID No: 20 and SEQ ID No: 21.
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