发明公开
- 专利标题： Genetic markers of mental illness
- 专利标题（中）： Genetische MarkerfürGeisteskrankheit
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申请号： EP12197030.5申请日： 2009-01-02
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公开(公告)号： EP2570497A2公开(公告)日： 2013-03-20
- 发明人: Brennan, Mark David , Ramsey, Timothy Lynn
- 申请人： Suregene Llc
- 申请人地址： 1044 East Chestnut Street, Suite 7 Louisville, KY 40204 US
- 专利权人： Suregene Llc
- 当前专利权人： Suregene Llc
- 当前专利权人地址： 1044 East Chestnut Street, Suite 7 Louisville, KY 40204 US
- 代理机构： Williams, Gareth Owen
- 优先权： US18534P 20080102; US21756P 20080117
- 主分类号： C12Q1/68
- IPC分类号： C12Q1/68
摘要：
This invention relates to genetic markers of mental illness, e.g., schizophrenia (SZ) and methods of use thereof. In particular, in vitro methods of predicting a human subject's likely response to treatment with olanzapine, risperidone, quetiapine, perphenazine or ziprasidone, or of selecting a treatment for schizophrenia comprising administration of olanzapine, risperidone, quetiapine, perphenazine or ziprasidone, comprising detecting a haplotype comprising one or more polymorphic markers in PCDH15 or markers in linkage desiquilbrium (LD) therewith, are provided.
公开/授权文献
- EP2570497B1 Genetic markers of mental illness 公开/授权日：2015-09-09
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