发明公开
EP2611777A1 4- { [ ( PYRIDIN- 3 - YL -METHYL) AMINOCARBONYL]AMINO} BENZENE - SULFONE DERIVATIVES AS NAMPT INHIBITORS FOR THERAPY OF DISEASES SUCH AS CANCER
有权
4 - {[（吡啶-3-基甲基）氨基羰基]氨基} -BENZOLSULFONDERIVATE NAMPT ALS抑制剂用于治疗疾病如癌症
- 专利标题： 4- { [ ( PYRIDIN- 3 - YL -METHYL) AMINOCARBONYL]AMINO} BENZENE - SULFONE DERIVATIVES AS NAMPT INHIBITORS FOR THERAPY OF DISEASES SUCH AS CANCER
- 专利标题（中）： 4 - {[（吡啶-3-基甲基）氨基羰基]氨基} -BENZOLSULFONDERIVATE NAMPT ALS抑制剂用于治疗疾病如癌症
-
申请号： EP11758024.1申请日： 2011-09-02
-
公开(公告)号： EP2611777A1公开(公告)日： 2013-07-10
- 发明人: BAIR, Kenneth W. , BAUMEISTER, Timm R. , BUCKMELTER, Alexandre J. , CLODFELTER, Karl H. , HAN, Bingsong , LIN, Jian , REYNOLDS, Dominic J. , SMITH, Chase C. , WANG, Zhongguo , ZHENG, Xiaozhang , YUEN, Po-Wai
- 申请人： Forma TM, LLC. , Genentech, Inc.
- 申请人地址： 500 Arsenal Street Suite 100 Watertown, MA 02472 US
- 专利权人： Forma TM, LLC.,Genentech, Inc.
- 当前专利权人： Forma TM, LLC.,Genentech, Inc.
- 当前专利权人地址： 500 Arsenal Street Suite 100 Watertown, MA 02472 US
- 代理机构： Bailey, Sam Rogerson
- 优先权： US201161480423P 20110429; US201161478995P 20110426; US386044P 20100924; US386037P 20100924; US379819P 20100903; US379812P 20100903
- 国际公布： WO2012031196 20120308
- 主分类号： C07D213/54
- IPC分类号： C07D213/54 ; C07D213/74 ; C07D213/75 ; C07D213/81 ; C07D213/84 ; C07D471/04 ; C07C317/00 ; A61K31/4406 ; A61K31/4433 ; A61K31/443 ; A61K31/4439 ; A61P35/00
摘要：
The present invention relates to compounds and compositions for the inhibition of NAMPT, their synthesis, applications and antidotes. An embodiment of the invention is the provision of a compound of Formula IIIA.
公开/授权文献
信息查询
