发明公开
- 专利标题： INDAZOLE DERIVATIVES USEFUL AS ERK INHIBITORS
- 专利标题（中）： INDAZOLDERIVATE ALS ERK-HEMMER
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申请号： EP11822418申请日： 2011-08-29
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公开(公告)号： EP2613782A4公开(公告)日： 2014-01-29
- 发明人: DENG YONGQI , SHIPPS GERALD W JR , LO SIE-MUN , ZHU LIANG , COOPER ALAN B , MUPPALLA KIRAN
- 申请人： MERCK SHARP & DOHME
- 专利权人： MERCK SHARP & DOHME
- 当前专利权人： MERCK SHARP & DOHME
- 优先权： US37917610 2010-09-01
- 主分类号： A61K31/416
- IPC分类号： A61K31/416 ; A61P35/00 ; C07D413/14 ; C07D417/12 ; C07D417/14 ; C07D491/113
摘要：
The present invention provides a compound of the Formula I: Formula I or a pharmaceutically acceptable salt, solvate or ester thereof, wherein R, R1, R2, R3, R4, X, m and n are as defined herein. The compounds are ERK inhibitors. Also disclosed are pharmaceutical compositions comprising the above compounds and methods of treating cancer using the same.
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