发明公开
- 专利标题: Compounds of lowering cholesterol
- 专利标题(中): 降低胆固醇的化合物
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申请号: EP13160192.4申请日: 2007-08-27
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公开(公告)号: EP2620147A2公开(公告)日: 2013-07-31
- 发明人: Goodenowe, Dayan
- 申请人: Phenomenome Discoveries Inc.
- 申请人地址: 204-407 Downey Road Saskatoon, Saskatchewan S7N 4L8 CA
- 专利权人: Phenomenome Discoveries Inc.
- 当前专利权人: Phenomenome Discoveries Inc.
- 当前专利权人地址: 204-407 Downey Road Saskatoon, Saskatchewan S7N 4L8 CA
- 代理机构: McConchie, Connor Fraser
- 优先权: US888883P 20070208
- 主分类号: A61K31/232
- IPC分类号: A61K31/232 ; A61K31/661 ; A61K31/6615 ; A61P3/06 ; G01N27/00 ; G01N33/483 ; G01N37/00 ; G01N33/68
摘要:
The present invention relates to a compound for use in lowering cholesterol, wherein the compound is selected from the group consisting of: DHAP; 1-acyl-DHAP; 1-alkyl-DHAP; 1-alkyl-G3P; 1-alkyl, 2-acyl-G3P; 1-alkyl, 2-acyl-glycerol; 1-alkyl, 2-acyl-GPE; I-alkyl, diacyl glycerol wherein sn-1=16:0, sn-2=DHA, sn-3=DHA, the sn-1 position has an alkyl ether bond, and the sn-2 and sn-3 positions have acyl bonds; 1-alkyl diacyl glycerol wherein sn-1=16:0, sn-2=18:1, sn-3=18:1, the sn-1 position has an alkyl ether bond, and the sn-2 and sn-3 positions have acyl bonds; triacyl glycerol wherein sn-1=16:0, sn-2=DHA, sn-3=DHA, and the sn-1, sn-2 and sn-3 positions have acyl bonds; and triacyl glycerol wherein sn-1=16:0, sn-2=18:1, sn-3=18:1, and the sn-1, sn-2 and sn-3 positions have acyl bonds; and pharmaceutically acceptable salts thereof.
公开/授权文献
- EP2620147B1 Compounds for lowering cholesterol 公开/授权日:2020-06-03
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