Various embodiments are disclosed that incorporate renal function check functionality in relation to contrast media injections. A contrast media injector system (430) may incorporate a data store (414) having a plurality of records (419), each of which includes data on contrast media type (416) and a corresponding threshold renal function (418). The contrast media injector system (430) and/or an imaging device (422) may incorporate a renal function assessment module (442). This module (442) may be configured with a protocol (480) that compares threshold renal function data with patient renal function data, and furthermore may be configured to only allow an injection to proceed if the patient renal function data complies with the relevant threshold renal function data. The threshold renal function data may be retrieved from a data storage device (516) incorporated by a syringe (504) installed on the contrast medical injector system (430).