发明公开
- 专利标题： ND2 PEPTIDES AND METHODS OF TREATING NEUROLOGICAL DISEASE
- 专利标题（中）： ND 2肽和用于治疗神经系统疾病
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申请号： EP11833072.9申请日： 2011-09-28
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公开(公告)号： EP2621945A2公开(公告)日： 2013-08-07
- 发明人: TYMIANSKI, Michael , LI, Rongwen , GARMAN, Jonathan David
- 申请人： NoNO Inc.
- 申请人地址： 88 Strath Avenue Toronto ON M8X 1R5 CA
- 专利权人： NoNO Inc.
- 当前专利权人： NoNO Inc.
- 当前专利权人地址： 88 Strath Avenue Toronto ON M8X 1R5 CA
- 代理机构： Elend, Almut Susanne
- 优先权： US387439P 20100928
- 国际公布： WO2012050921 20120419
- 主分类号： C07K14/47
- IPC分类号： C07K14/47 ; C07K19/00 ; A61K38/17 ; A61P25/00 ; A61P35/00
摘要：
The invention is based in part on identifying a core region of ND2 responsible for interacting with Src to within residues 289-321 of ND2 and more particularly residues 310-321 of ND2. Peptides including, overlapping or from within this region can be used to inhibit ND2 interaction with Src. Inhibition of this interaction is useful for treatment or prophylaxis of neurological diseases and disorders, pain and cancer.
公开/授权文献
- EP2621945B1 ND2 PEPTIDES AND METHODS OF TREATING NEUROLOGICAL DISEASE 公开/授权日：2018-04-11
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