发明公开
EP2630240A1 COMPOSITIONS AND METHODS FOR INHIBITING EXPRESSION OF RRM2 GENES
审中-公开
ZUSAMMENSETZUNGEN UND VERFAHREN ZUR HEMMUNG DER EXPRESSION VON RRM2-GENEN
- 专利标题： COMPOSITIONS AND METHODS FOR INHIBITING EXPRESSION OF RRM2 GENES
- 专利标题（中）： ZUSAMMENSETZUNGEN UND VERFAHREN ZUR HEMMUNG DER EXPRESSION VON RRM2-GENEN
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申请号： EP11767402.8申请日： 2011-09-27
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公开(公告)号： EP2630240A1公开(公告)日： 2013-08-28
- 发明人: BOYLAN, John Frederick , BRAMLAGE, Birgit , HOSSBACH, Markus , REIDHAAR-OLSON, John
- 申请人： Arrowhead Research Corporation
- 申请人地址： 225 South Lake Avenue Suite 1050 Pasadena, CA 91101 US
- 专利权人： Arrowhead Research Corporation
- 当前专利权人： Arrowhead Research Corporation
- 当前专利权人地址： 225 South Lake Avenue Suite 1050 Pasadena, CA 91101 US
- 代理机构： van Kooij, Adriaan
- 优先权： EP10187851 20101018
- 国际公布： WO2012052258 20120426
- 主分类号： C12N15/113
- IPC分类号： C12N15/113 ; A61P35/00
摘要：
The invention relates to a double-stranded ribonucleic acid (dsRNA) for inhibiting the expression of a RRM2 gene. The invention also relates to a pharmaceutical composition comprising the dsRNA or nucleic acid molecules or vectors encoding the same together with a pharmaceutically acceptable carrier; methods for treating diseases caused by the expression of a RRM2 gene using said pharmaceutical composition; and methods for inhibiting the expression of RRM2 in a cell.
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