发明公开
- 专利标题: FELBINAC-CONTAINING EXTERNAL PATCH
- 专利标题(中): FELBINAC-包含外部补丁
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申请号: EP11838026.0申请日: 2011-11-01
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公开(公告)号: EP2636405A1公开(公告)日: 2013-09-11
- 发明人: INOO, Katsuyuki
- 申请人: Teikoku Seiyaku Co., Ltd.
- 申请人地址: 567 Sanbonmatsu Higashikagawa-shi, Kagawa 769-2695 JP
- 专利权人: Teikoku Seiyaku Co., Ltd.
- 当前专利权人: Teikoku Seiyaku Co., Ltd.
- 当前专利权人地址: 567 Sanbonmatsu Higashikagawa-shi, Kagawa 769-2695 JP
- 代理机构: Albrecht, Thomas
- 优先权: JP2010246666 20101102
- 国际公布: WO2012060376 20120510
- 主分类号: A61K31/192
- IPC分类号: A61K31/192 ; A61K9/70 ; A61K47/14 ; A61K47/32 ; A61P29/00
摘要:
Provided is a felbinac-containing external patch which can exhibit high drug release properties, low skin irritation, and high drug stability, wherein felbinac having an average particle diameter of 5 µm or more and less than 100 µm is dispersed and mixed in an adhesive base including a styrene-isoprene-styrene block copolymer, an alicyclic saturated hydrocarbon resin, a softener, and diethyl sebacate, and does not contain L-menthol. Specifically, in the felbinac-containing external patch, 0.1 to 10% by weight of felbinac having an average particle diameter of 5 µm or more and less than 100 µm is dispersed and mixed in an adhesive base including 10 to 30% by weight of a styrene-isoprene-styrene block copolymer, 10 to 50% by weight of an alicyclic saturated hydrocarbon resin, 10 to 75% by weight of a softener, and 0.1 to 10% by weight of diethyl sebacate.
公开/授权文献
- EP2636405B1 FELBINAC-CONTAINING EXTERNAL PATCH 公开/授权日:2018-03-14
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