发明公开
EP2640709A2 PYRIMIDINE HYDROXY AMIDE COMPOUNDS AS PROTEIN DEACETYLASE INHIBITORS AND METHODS OF USE THEREOF
有权
PYRIMIDINHYDROXY酰胺化合物ALS PROTEINDEACETYLASE抑制剂和使用它们的方法
- 专利标题： PYRIMIDINE HYDROXY AMIDE COMPOUNDS AS PROTEIN DEACETYLASE INHIBITORS AND METHODS OF USE THEREOF
- 专利标题（中）： PYRIMIDINHYDROXY酰胺化合物ALS PROTEINDEACETYLASE抑制剂和使用它们的方法
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申请号： EP11840803.8申请日： 2011-11-15
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公开(公告)号： EP2640709A2公开(公告)日： 2013-09-25
- 发明人: VAN DUZER, John, H. , MAZITSCHEK, Ralph , DING, Yanbing , YU, Nan , CAO, Yun , LIU, Yong
- 申请人： Acetylon Pharmaceuticals, Inc.
- 申请人地址： 70 Fargo Street, Suite 205 Boston, MA 02210 US
- 专利权人： Acetylon Pharmaceuticals, Inc.
- 当前专利权人： Acetylon Pharmaceuticals, Inc.
- 当前专利权人地址： 70 Fargo Street, Suite 205 Boston, MA 02210 US
- 代理机构： Boult Wade Tennant
- 优先权： US201161503286P 20110630; US414158P 20101116
- 国际公布： WO2012068109 20120524
- 主分类号： C07D239/12
- IPC分类号： C07D239/12 ; C07D239/16 ; C07D409/12 ; A61K31/495 ; A61P25/00
摘要：
The present invention relates to novel pyrimidine hydroxy amide compounds, and the use of such compounds in the inhibition of HDAC6 and in the treatment of various diseases, disorders or conditions related to HDAC6.
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