发明公开
EP2640749A1 SILENT FC VARIANTS OF ANTI-CD40 ANTIBODIES 有权
仍然是FC-VARIANTEN VON ANTI-CD40-ANTIKÖRPERN

  • 专利标题: SILENT FC VARIANTS OF ANTI-CD40 ANTIBODIES
  • 专利标题(中): 仍然是FC-VARIANTEN VON ANTI-CD40-ANTIKÖRPERN
  • 申请号: EP11781571.2
    申请日: 2011-11-14
  • 公开(公告)号: EP2640749A1
    公开(公告)日: 2013-09-25
  • 发明人: HEUSSER, ChristophRUSH, JamesVINCENT, Karen
  • 申请人: Novartis AG
  • 申请人地址: Lichtstrasse 35 4056 Basel CH
  • 专利权人: Novartis AG
  • 当前专利权人: Novartis AG
  • 当前专利权人地址: Lichtstrasse 35 4056 Basel CH
  • 代理机构: Fredh, Fredrik
  • 优先权: US413567P 20101115
  • 国际公布: WO2012065950 20120524
  • 主分类号: C07K16/28
  • IPC分类号: C07K16/28
SILENT FC VARIANTS OF ANTI-CD40 ANTIBODIES
摘要:
The present invention relates to silent Fc variants of anti-CD40 antibodies and compositions and methods of use of said antibodies for treating pathological disorders such as autoimmune and inflammatory disorders and/or for preventing or reducing the risk of graft rejection in transplantation.
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