发明公开
- 专利标题: SILENT FC VARIANTS OF ANTI-CD40 ANTIBODIES
- 专利标题(中): 仍然是FC-VARIANTEN VON ANTI-CD40-ANTIKÖRPERN
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申请号: EP11781571.2申请日: 2011-11-14
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公开(公告)号: EP2640749A1公开(公告)日: 2013-09-25
- 发明人: HEUSSER, Christoph , RUSH, James , VINCENT, Karen
- 申请人: Novartis AG
- 申请人地址: Lichtstrasse 35 4056 Basel CH
- 专利权人: Novartis AG
- 当前专利权人: Novartis AG
- 当前专利权人地址: Lichtstrasse 35 4056 Basel CH
- 代理机构: Fredh, Fredrik
- 优先权: US413567P 20101115
- 国际公布: WO2012065950 20120524
- 主分类号: C07K16/28
- IPC分类号: C07K16/28
摘要:
The present invention relates to silent Fc variants of anti-CD40 antibodies and compositions and methods of use of said antibodies for treating pathological disorders such as autoimmune and inflammatory disorders and/or for preventing or reducing the risk of graft rejection in transplantation.
公开/授权文献
- EP2640749B1 SILENT FC VARIANTS OF ANTI-CD40 ANTIBODIES 公开/授权日:2017-04-19
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