发明公开
- 专利标题: METHODS OF TREATMENT USING SELECTIVE BCL-2 INHIBITORS
- 专利标题(中): 治疗方法使用选择性bcl-2抑制剂
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申请号: EP11793928.0申请日: 2011-11-22
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公开(公告)号: EP2642999A1公开(公告)日: 2013-10-02
- 发明人: ELMORE, Steven , SOUERS, Andrew , WANG, Li Chun , GHAYUR, Tariq , PERPER, Stuart J.
- 申请人: AbbVie Inc.
- 申请人地址: 1 North Waukegan Road North Chicago, IL 60064 US
- 专利权人: AbbVie Inc.
- 当前专利权人: AbbVie Inc.
- 当前专利权人地址: 1 North Waukegan Road North Chicago, IL 60064 US
- 代理机构: Modiano, Micaela Nadia
- 优先权: US416689P 20101123
- 国际公布: WO2012071374 20120531
- 主分类号: A61K31/496
- IPC分类号: A61K31/496 ; A61P37/00
摘要:
This invention pertains to methods of treating systemic lupus erythematosus, lupus nephritis or Sjogren's Syndrome with compounds that selectively inhibit the activity of Bcl-2 anti-apoptotic proteins. Specifically, the current invention is directed to treatment with compounds that selectively inhibit the activity of Bcl-2 proteins, with a lesser affinity for inhibiting the activity of other BCL-2 family proteins, including Bcl-x L .
公开/授权文献
- EP2642999B1 METHODS OF TREATMENT USING SELECTIVE BCL-2 INHIBITORS 公开/授权日:2016-09-28
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