发明公开
EP2655334A1 COMPOSITIONS AND METHODS USEFUL FOR TREATING DISEASES
审中-公开
ZUSAMMENSETZUNGEN UND VERFAHREN ZUR BEHANDLUNG VON ERKRANKUNGEN
- 专利标题： COMPOSITIONS AND METHODS USEFUL FOR TREATING DISEASES
- 专利标题（中）： ZUSAMMENSETZUNGEN UND VERFAHREN ZUR BEHANDLUNG VON ERKRANKUNGEN
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申请号： EP11851853.9申请日： 2011-12-22
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公开(公告)号： EP2655334A1公开(公告)日： 2013-10-30
- 发明人: CARDONE, Michael H. , YU, Xiang Y. , KOLODZIEJ, Andrew F.
- 申请人： Eutropics Pharmaceuticals, Inc.
- 申请人地址： 767-C Concord Avenue Cambridge, Massachusetts 02138 US
- 专利权人： Eutropics Pharmaceuticals, Inc.
- 当前专利权人： Eutropics Pharmaceuticals, Inc.
- 当前专利权人地址： 767-C Concord Avenue Cambridge, Massachusetts 02138 US
- 代理机构： Grund, Martin
- 优先权： US201061425909P 20101222
- 国际公布： WO2012088438 20120628
- 主分类号： C07D233/56
- IPC分类号： C07D233/56 ; C07D233/58
摘要：
The present invention relates to a chemotherapeutic cancer treatment in which compounds of Formula la', lb', Ic', or II' (referred to as a group as BH3ls) are administered to a mammal for the treatment of B-cell Lymphoma or other hematopoietic cancers, including diseases associated with MeL-l. In another aspect, the invention provides a method for treating particular types of hematopoietic cancers, such as B-cell lymphoma, using a combination of one or more compounds selected from the group consisting of compounds of la', lb', Ic', or II' in combination with other therapies, for example, a class of therapeutics known as 26S proteosome inhibitors, such as, for example, Bortezomib. In another aspect the present invention relates to autoimmune treatment with pharmaceutical compositions comprising one or more compounds of Formula la', lb', Ic', or II'.
公开/授权文献
- EP2655334B1 COMPOSITIONS AND METHODS USEFUL FOR TREATING DISEASES 公开/授权日：2018-10-03
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