The disclosure relates to methods and apparatuses that facilitate power and quality control of uplink MIMO transmissions. A method in a NodeB comprises controlling (50) transmission power of multiple pilot signals transmitted by a user equipment by using a single inner power control loop operating on at least one pilot signal of the multiple pilot signals. Some disclosed embodiments also relate to adjustment (60) of a quality target applied by the single inner power control loop and to updating (71, 72) of a power offset for computing the number of bits that the user equipment can transmit on a stream that is associated with a pilot signal that is not power controlled by the single inner power control loop.