发明公开
- 专利标题： ELUENT SOLUTION
- 专利标题（中）： ELUIERUNGSLÖSUNG
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申请号： EP11808853.3申请日： 2011-12-21
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公开(公告)号： EP2658831A1公开(公告)日： 2013-11-06
- 发明人: WICKSTROM, Torild , SVADBERG, Anders , HJELSTUEN, Ole Kristian , EVJE, Dag, M. , OCHSENFELD, Liane
- 申请人： GE Healthcare UK Limited
- 申请人地址： Amersham Place Little Chalfont Buckinghamshire HP7 9NA GB
- 专利权人： GE Healthcare UK Limited
- 当前专利权人： GE Healthcare UK Limited
- 当前专利权人地址： Amersham Place Little Chalfont Buckinghamshire HP7 9NA GB
- 代理机构： Bannan, Sally
- 优先权： US201061427839P 20101229
- 国际公布： WO2012089594 20120705
- 主分类号： C07B59/00
- IPC分类号： C07B59/00
摘要：
The present invention provides a novel method for the preparation of
18 F-fluoride (
18 F) for use in radiofluorination reactions. The method of the invention finds use especially in the preparation of
18 F-labelled positron emission tomography (PET) tracers. The method of the invention is particularly advantageous where bulk solutions are prepared and stored in prefilled vials rather than being freshly prepared on the day of synthesis. Also provided by the present invention is a radiofluorination reaction which comprises the method of the invention, as well as a cassette for use in carrying out the method of the invention and/or the radiofluorination method of the invention on an automated radiosynthesis apparatus.
18 F-fluoride (
18 F) for use in radiofluorination reactions. The method of the invention finds use especially in the preparation of
18 F-labelled positron emission tomography (PET) tracers. The method of the invention is particularly advantageous where bulk solutions are prepared and stored in prefilled vials rather than being freshly prepared on the day of synthesis. Also provided by the present invention is a radiofluorination reaction which comprises the method of the invention, as well as a cassette for use in carrying out the method of the invention and/or the radiofluorination method of the invention on an automated radiosynthesis apparatus.
公开/授权文献
- EP2658831B1 ELUENT SOLUTION 公开/授权日：2017-02-15
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