发明公开
EP2708597A4 POLYNUCLEATED MEGAKARYOCYTIC CELL AND METHOD FOR MANUFACTURING PLATELETS
有权
POLYNUKLEIERTE巨核细胞及其制造方法血小板
- 专利标题： POLYNUCLEATED MEGAKARYOCYTIC CELL AND METHOD FOR MANUFACTURING PLATELETS
- 专利标题（中）： POLYNUKLEIERTE巨核细胞及其制造方法血小板
-
申请号： EP12785650申请日： 2012-05-11
-
公开(公告)号： EP2708597A4公开(公告)日： 2014-11-19
- 发明人: ETO KOJI , NAKAUCHI HIROMITSU , TAKAYAMA NAOYA , NAKAMURA SOU
- 申请人： UNIV TOKYO
- 专利权人： UNIV TOKYO
- 当前专利权人： UNIV TOKYO
- 优先权： JP2011108253 2011-05-13
- 主分类号： C12N5/10
- IPC分类号： C12N5/10 ; A61K35/14 ; A61P7/00 ; C12N15/09
摘要：
An object of the present invention is to provide a method of promoting polyploidization of megakaryocytes and thereby producing highly polyploidized megakaryocytes, a method of efficiently producing platelets from polyploidized megakaryocytes, and the like. The present invention provides a method of producing polyploidized megakaryocytes comprising a step of forcing expression of an apoptosis suppressor gene in megakaryocytes before polyploidization and culturing the resulting cells.
信息查询
