发明公开
EP2709630A1 PAR1 INHIBITORS FOR USE IN THE TREATMENT OR PREVENTION OF PARAMYXOVIRIDAE INFECTIONS
审中-公开
PAR1抑制剂FOR USE IN感染副粘病毒治疗或预防
- 专利标题: PAR1 INHIBITORS FOR USE IN THE TREATMENT OR PREVENTION OF PARAMYXOVIRIDAE INFECTIONS
- 专利标题(中): PAR1抑制剂FOR USE IN感染副粘病毒治疗或预防
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申请号: EP12782732.7申请日: 2012-05-11
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公开(公告)号: EP2709630A1公开(公告)日: 2014-03-26
- 发明人: RITEAU, Béatrice , BOIVIN, Guy , AERTS, Laetitia , HAMELIN, Marie-Eve
- 申请人: Université Laval , Institut National de la Recherche Agronomique (INRA)
- 申请人地址: Vice-rectorat à la recherche et à la création Pavillon des Sciences de l'Education 2320, Rue des Bibliothèques, Local 1434 Quebec, QC G1V 0A6 CA
- 专利权人: Université Laval,Institut National de la Recherche Agronomique (INRA)
- 当前专利权人: Université Laval,Institut National de la Recherche Agronomique (INRA)
- 当前专利权人地址: Vice-rectorat à la recherche et à la création Pavillon des Sciences de l'Education 2320, Rue des Bibliothèques, Local 1434 Quebec, QC G1V 0A6 CA
- 代理机构: Regimbeau
- 优先权: US201161485419P 20110512
- 国际公布: WO2012151687 20121115
- 主分类号: A61K31/5377
- IPC分类号: A61K31/5377 ; A61K31/443 ; A61K31/517 ; A61P31/14 ; A61K31/7088 ; A61K39/395
摘要:
The present invention is concerned with the use of Protease-Activated Receptor-1 (PAR1) inhibitors for preventing or treating a Paramyxoviridae infection in a subject. Described herein are methods, compounds and pharmaceutical compositions useful in addressing such infections, and more particularly infections from human respiratory syncytial virus (hRSV) and human metapneumovirus (hMPV).
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